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Les anticholinergiques constituent la pierre angulaire du traitement de cette affection. De plus, ils ont tous des effets secondaires. Ils correspondent aux cinq sous-types M1—M5 8.

Tableau 1. M3 Muscle lisse, glandes et cerveau. M4 Cerveau. Dmochowski et coll. Lehtoranta et coll. Chlorure de trospium Le chlorure de trospium Ceris 20 mg, Madaus, Sanctura 20 mg, Sanctura XR 60 mg, Allergan est connu sous le nom de Benziloyloxy-3 spiro[azonia-8 bicyclo[3. Zinner et coll. Cardozo et coll. Chapple et coll. Bibliographie 1. The standardisation of terminology in lower urinary tract function: report from the standardisation sub-committee of the International Continence Society.

Effectiveness of anticholinergic drugs compared with placebo in the treatment of overactive bladder. DOI : Estimated economic costs of overactive bladder in the United States.

Wyndaele J-J. Fesoterodine: Individualised treatment of urgency urinary incontinence across patient groups. Eur Urol Supplements. Diaa E, Rizk E. Pharmacological therapy of female urinary incontinence. African Health Sciences. Incont Pelvic Floor Dysfunct. Anderson K. Potential benefic of muscarinic M3 receptor selectivity. International Union of Pharmacology. Classification of muscarinic acetylcholine receptors.

Pharmacol Rev. Expression of muscarinic M3-receptors coupled to inositol phospholipids hydrolysis in human detrusor cultured smooth muscle cells. J Urol. Evaluation of mRNAs encoding muscarinic receptor subtypes in human detrusor muscle. Brading AF. A myogenic basis for the overactive bladder.

Overactive bladder: Why it occurs. Brading AF, Symes S. Ischemia as an etiological factor in bladder instability: Implications for therapy. Adv Exp Med Biol. Physiological and morphometric studies into the pathophysiology of detrusor hyperreflexia in neuropathic patients. Sibley GN. Developments in our understanding of detrusor instability. Br J Urol. De Groat WC. A neurologic basis for the overactive bladder.

Model of peripheral autonomous modules and a myovesical plexus in normal and overactive bladder function. Gillespie JI. The autonomous bladder: A view of the origin of bladder overactivity and sensory urge. BJU Int. Hegde Sharath S. Muscarinic receptors in the bladder: from basic research to therapeutics. Br J Pharmacol. Andersson KE. Current concepts in the treatment of disorders of micturition. Kristen H. Agents for treatment of overactive bladder: a therapeutic class review.

Proc Bayl Univ Med Cent ;— The pharmacological treatment of urinary incontinence. Br J Urol Int. Wein AJ. Pharmacology of incontinence. Urol Clin North Am. Measurement of oxybutynin and its N-desethyl metabolite in plasma, and its application to pharmacokinetic studies in young, elderly and frail elderly volunteers. Nilvebrant L, Sparf B. Dicyclomine, benzhexol and oxybutynin distinguish between subclasses of muscarinic binding sites.

Eur J Pharmacol. Propiverine compared to oxybutinin in neurogenic detrusor overactivity-results of a randomized, double blind, multicenter clinical study. Eur Urol.


Anticholinergiques centraux et périphériques (antispasmodiques)


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Les antispasmodiques



Antispasmodiques anticholinergiques


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