En ensayos de grandes dimensiones sehizo cada 6 a 12 meses. Estudios recientes con etoricoxib han demostrado un perfil deseguridad similar al diclofenac, pero probablemente inferior al naproxeno. AINEs tradicionalesEn los ensayos controlados contra rofecoxib y lumiracoxib, naproxeno hamostrado una menor incidencia de complicaciones cardiovasculares, lo que no seha observado con ibuprofeno o diclofenac. Posible mecanismo:vasoespasmo. Mejoran con IECA.
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CARDIOTOXICIDAD POR QUIMIOTERAPIA PDF
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Toxicidad de los tratamientos oncológicos
Tratamiento del cáncer sin daño al corazón
Toxicidad de los tratamientos oncológicos