Chronotherapeutic combinations of light and wake therapy achieve fast results and, by reducing residual symptoms, also minimise relapse. This manual introduces chronotherapeutics for depression, a new synthesis of non-pharmacologic interventions designed to accelerate remission in bipolar and unipolar patients alike. It examines the underlying clinical research, explains the involvement of the circadian timing system, and provides hands-on instructions for treating inpatients and outpatients. Written by three of the most prominent experts in the research and clinical applications of chronotherapy, this book enables clinicians to implement its principles and let their patients benefit from its practicality and effectiveness.
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Download Pathophysiological Phenomena in Nursing: Human Responses to Illness synthesizes the latest knowledge and understanding about human responses to a range of significant biological processes, symptoms, and clinical manifestations of illness. This advanced text provides a basis for developing or examining the current knowledge and evidence base for nursing practice in these important areas across the age and health-illness continuums.
Examination of each of the 21 phenomena covered within the sections includes definition, prevalence, populations at risk, risk factors environmental, personal, and developmental , mechanisms, pathological consequences, related pathophysiological concepts, differential diagnosis, manifestations, surveillance, clinical management, conceptual model s , case studies, selected research, and questions for future study.
Uses a conceptual approach to examining and understanding 21 common clinical problems to help nurses focus on phenomena they encounter frequently across disease and illness categories and across settings.
Focuses on human responses to illness in adult and older adult populations to assist the nurse to develop, test, implement and evaluate clinical therapies to prevent or alleviate these responses. Presents state-of-the-art, evidence-based knowledge related to each physiological phenomena to help nurses develop the knowledge base needed to deliver the most effective care possible.
Offers a conceptual foundation for the study of human responses and clinical pathophysiological phenomena from which to teach and learn the science of nursing.
Provides a baseline of conceptual, research-based information from which to design further investigations. Provides empirical support for nursing theory development and further research.
Follows a consistent organization within each chapter to enable the reader to easily locate desired information. Includes case studies to link chapter content with real-world patient encounters. Addresses addiction in a separate chapter to accommodate expanded coverage of this topic. Introduces a new section, Cognition, featuring separate new chapters on dementia and acute confusion. Search for:.
Chronotherapeutics for affective disorders: A clinician's manual for light and wake therapy
Psychol Med. Treatment can be a single or repeated sleep deprivation, total all night or partial second half of the night. Relapse can be prevented by daily light therapy, concomitant administration of SSRIs, lithium for bipolar patients , or a short phase advance of sleep over 3 days following a single night of wake therapy. Combinations of these interventions show great promise. Light therapy is effective for major depression--not only for the seasonal subtype.
Chronotherapeutics (light and wake therapy) in affective disorders.
This article has been cited by other articles in PMC. Abstract Chronotherapeutics refers to treatments based on the principles of circadian rhythm organization and sleep physiology, which control the exposure to environmental stimuli that act on biological rhythms, in order to achieve therapeutic effects in the treatment of psychiatric conditions. It includes manipulations of the sleep-wake cycle such as sleep deprivation and sleep phase advance, and controlled exposure to light and dark. The antidepressant effects of chronotherapeutics are evident in difficult-to-treat conditions such as bipolar depression, which has been associated with extremely low success rates of antidepressant drugs in naturalistic settings and with stable antidepressant response to chronotherapeutics in more than half of the patients. The need for chronotherapeutics Chronotherapeutics refers to treatments based on the principles of circadian rhythm organization and sleep physiology, 1 , 2 which control the exposure to environmental stimuli that act on biological rhythms, in order to achieve therapeutic effects in the treatment of psychiatric conditions. The use of these techniques in everyday clinical practice is almost exclusively limited to the treatment of mood disorders, offering mental health practitioners a set of nonpharmaceutical, rapid, and effective antidepressant modalities for monotherapy or as adjuvants to conventional medication. The present review focuses on recent achievements in the chronotherapeutic treatment of bipolar depression and on the recently discovered molecular mechanisms that clearly link chronotherapeutics with the usual antidepressant drug treatments of this disorder.
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