The mean age at baseline was About The incidence of prior stroke was 6. The study was terminated early, when the second planned interim analysis showed a significant reduction in the incidence of strokes, as well as total mortality in the indapamide arm. At the end of the trial, 1, patients were still undergoing double-blind follow-up..
Mabei Special considerations In older patients, left diastolic ventricular dysfunction associated with elevated flling pressures is observed and may lead to secondary pulmonary hypertension. Closure of secundum atrial septal defects with the Amplatzer septal occluder device: The role of echocardiography during interventional procedures is well documented 3,4 and several techniques have been described for the guidance of PTC of ASD.
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